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Desktop Printers

ZD420 Thermal Transfer Ribbon Cartridge Desktop Printer Support



The ZD420 printers (Standard and Healthcare) are part of the ZD400 Series Printer family

Zebra is no longer offering this product for sale. The product resources are provided below for your use and convenience. Please note that Customer Support will not be available after the Service and Support Discontinuation date. If you require additional support, please contact a Zebra Authorized Service Provider.

Printer Discontinuation Date: December 31, 2021 
Service & Support Discontinuation Date: February 28, 2025

Printer Discontinuation Date: September 30, 2021 
Service & Support Discontinuation Date: November 29, 2024

North America
Printer Discontinuation Date: September 30, 2021 
Service & Support Discontinuation Date: December 31, 2024

Latin America
Printer Discontinuation Date: January 31, 2022 
Service & Support Discontinuation Date: April 30, 2025

ZD420c Desktop Printer


The Setup guidelines below will take you to English documentation. You can access the localized User Guides in the DOCUMENTATION tab.

IMPORTANT! Do not connect your printer to a computer yet! 

  • If you connected your printer to a computer via USB before driver installation, the printer might appear as an unknown (unspecified) device in “Devices and Printers.” 
  • If necessary, follow these recovery steps before proceeding to Step 1. 

1. Download and install the recommended Windows Printer Driver v10.

2. Download and install the Zebra Setup Utilities (ZSU) printer configuration utility.

3. Connect the printer to a USB port on your computer and power up it .

4. Load media (media usually means labels, but it also includes tag stock, receipt paper, and other things that can be printed on).

  • You can watch the video in the VIDEOS tab.
  • The media settings must match the actual media that you are using. 
    How to identify media type.

5. When using thermal transfer media, insert the ribbon cartridge.

  • You can watch the video available in the VIDEOS tab.
  • How to find out if you have thermal transfer media?
    Do a media scratch test.

6. Run a SmartCal media calibration and print a configuration report. Videos are also available in the HOW-TO VIDEOS section below.

7. Manually calibrate ribbon and media sensors.

  • When changing the size or type of media. 
  • If printing issues are observed, such as skipped labels, vertical image/label drift, or media out errors.
  • You can watch the video in the VIDEOS tab.

8. The printer settings must match the actual supplies that you are using for your print job and the options on your printer. Adjust the printer settings as necessary using Zebra Setup Utilities software or Windows Printer Driver v8

*Additional User Manuals relating to hardware and connectivity options are available in English in the DOCUMENTATION tab. 


Software that is essential for operating and connecting this device. 

I agree to and accept the above terms and conditions.

If you connected your printer to the computer via USB before driver installation, follow these recovery steps before printer driver installation. 


Some documents may not have been translated to your language.


ZD420 How-to Videos

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For some services, you will need a serial number. Here's where you can find it on your device.