Chat with us
Establishing connection, please wait while we connect you.

The new and improved Support and Downloads pages are now live! You asked, and we listened. Visit the Support and Downloads Experience page to learn more about this update.

Desktop Printers

ZD421 Series Printer Support



The ZD411 printer is part of the ZD400 Series Printer family.

Retain proof of purchase for warranty confirmation.

ZD421 Desktop Printer

ZD421C, ZD421T, ZD421D

The Setup guidelines below will take you to English documentation. You can access the localized User Guides in the DOCUMENTATION tab.

IMPORTANT! Do not connect your printer to a computer yet! 

  • If you connected your printer to a computer via USB before driver installation, the printer might appear as an unknown (unspecified) device in “Devices and Printers.” 
  • If necessary, follow these recovery steps before proceeding to Step 1. 

1. Download and install the recommended Windows Printer Driver v10.

2. Download and install the Zebra Setup Utilities (ZSU) printer configuration utility.

3. Connect the printer to a USB port on your computer and power up.

4. Load media (media usually means labels, but it also includes tag stock, receipt paper, and other things that can be printed on).

  • You can watch the video in the VIDEOS tab.
  • The media settings must match the actual media that you are using. 
    How to identify media type.

5. When using thermal transfer media, load ribbon or insert ribbon cartridge.

  • This step does not apply to the ZD421 direct thermal printer.
  • You can watch the videos in the VIDEOS tab.
  • How to find out if you have thermal transfer media?

Do a media scratch test.

6. Run a SmartCal media calibration and print a configuration report. Videos are also available in the VIDEOS tab.

7. Manually calibrate ribbon and media sensors. 

  • When changing the size or type of media. 
  • If printing issues are observed, such as skipped labels, vertical image/label drift, or media out errors.

8. The printer settings must match the actual supplies that you are using for your print job and the options on your printer. Adjust the printer settings as necessary using Zebra Setup Utilities software or Windows Printer Driver v8

*Additional User Manuals relating to hardware and connectivity options are available in English in the DOCUMENTATION tab.


Software that is essential for operating and connecting this device. 

I agree to and accept the above terms and conditions.

If you connected your printer to the computer via USB before driver installation, follow these recovery steps before printer driver installation. 


Some documents may not have been translated to your language.


ZD421 Thermal Transfer Printer How-to Videos


ZD421 Direct Thermal Printer How-to Videos


ZD421 Ribbon Cartridge Printer How-to Videos

Trending Articles

Application Software

Zebra software products that can enhance your experience with this device. 

Warranty and Repair

For some services, you will need a serial number. Here's where you can find it on your device.